Today the seizure like attack happened even though he is on the steroids. She seems to be feeling better but still very concerned of why these levels are still up. My vet seems skeptical that this is related to simparica but it seems clear to me, although I realize that anecdotal cases don't prove it. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. This medication is generally well tolerated in most pets. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death. We started the medication on Dec. 1st and 3 days later it started with vomiting and loss of appetite. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. He was vomiting, had diarrhea, urinating constantly and the very scary part were the uncontrollable tremors. That was when I lived in Fort Lauderdale. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. Severity: Severity is mild to moderate to severe Read more. I'm more concerned about fleas and heartworms and Trifexis is just fine for that. Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? . Both of them aren't eating like they were. I want to thank everyone who posted I could not find enough information on other sites. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick "remedy" and already several dogs have been adversely affected by this new drug. Maybe dont have a dog. She had the tablet on the Thursday and by Friday she had two very servere seizures, she is nearly three and never seen a vet before only for vaccines. I wish I would have researched this before giving it to my puppy who is only 10 weeks, he has the same symptoms . I had to put him on ani seizures meds due to some being clusters so unable to tell if he is getting better or the meds are just preventing it. If it has been a long period of time since the last dose was given, you may see fleas temporarily during the missed time. In addition to the tremors, have you noticed any . If most side effects are mild, ( vomiting 12 hours later could be due to other things the dog has eaten within those 12 hours), I am ok with that. It kills heartworm larvae by causing paralysis that leads to the death of the parasite. So this month. Nothing they can do for her she said. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. We will have blood work and results this evening. Gave my 3 month old, 3 pound shih tzu simparica on Sunday night. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). Barely eats, but is drinking lots of water. Still waiting on the vet and waiting to talk to ASPCA poison control. Thank u Fox I have good news I did get 2 additional in house potassium test done and they both came back normal. The other has had diarrhea every since 6 hours after the pill. . Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. How common are Simparica side effects? She vomited twice and became so lethargic that she couldnt walk. I just almost had a similar incident with my 16wk cavapoo. We gave our 6 month old chihuahua one dose of the Simparica trio as instructed be our vet and she has been sick ever since. Hi there, So sorry to hear about your dog. I hope this drug has not caused permanent damage. Vet says Simparica is not the reason for his condition, but he was totally fine prior to taking Simparica!! and now i'm on an hour by hour let's see if she will perk up. 12/18/21.. he did experience some diarrhea. I am trying to remain confident that my poor girl will recover. So sorry! When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. Head down, tail down, will stand in a corner and stare at the wall. Monday morning - 11 days after he is like a zombie - all motions are almost mechanical and when I talk to him it takes him a long while to react. We took him to vet and they gave nausea meds and kept him overnight. Hes not well..we hope he recovers fully! She became extremely lethargic and feverish so we rushed her to Hospital. He had his second dose on 3rd July. And my 1 year old cockapoo has been having regular seizures and her blood work has come back indicative of liver dysfunction. This Tuesday the 17th I had given my dog simparica trio for 27lbs dose. Simparica has possibly shown no severe side effects that may concern the health of dogs. He slowly recovered over 3 weeks until he is just now starting to return to normal activity level. UPDATE We had one normal day on Friday. The office girl not the vet said if it my dog threw up within one hour after eating her pill - then it is safe to give her another one. These dog training tips will help you get started. Hopefully yours will be lucky and return to normal. Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. To make dosing easy, it's available for dogs in six sizes based on body weight range: Simparica Trio can be given to dogs with or without food. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! I'm besides myself. Two months no flare up no more scabs and loosing hair. All the swelling went down immediately and the itching went away too. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. I wish I would have came across this before I gave my healthy 9 month old puppy this medication two days ago. And has been for about 3 weeks. I would notice he gets super tired walking and would go limp in my arms. I wish I could get it out of her system. This is so awful. Nexgard can cause lethargy and a loss of appetite in dogs. The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. I gave this trash to my 5 month old JRT yesterday. My dog is having the same issues. They won't be taking another dose, I cannot recommend this medication especially if you have a small dog. However, they are possible, so it is better to know they might happen. You ask why they are giving this poison to our furbabies, it's easy. Then I saw this and realized. I wouldnt have given it to her. 5 hours after the dose she's home resting. Does anyone know of anything we can give her to help get this out of her system? We are experiencing the same thing. Took a dose of simparica trio.second rose in second month.dog is having tremors. Im throwing away the remaining 5 pills and going back to a topical medicine. Thank you all for speaking out on Simparica Trio that Bandfield Hospital pushed on our Toy Poodle. Once again peed in my office on Saturday. So, I gave it to him. Simparica Trio works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and hookworms. four times. Now I am terrified for his well being. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. I have an 8 year old Labrador. Then gave me pills of prednisone for him to take 1 pill twice a day . My dog has been vomiting with diarrhea plus he has bumps all over his body from one dose of simparica trio. Is it effective? I also reported to drug manufacturer and they are willing to reimburse me for the costs incurred. Trifexis and Simparica are available only with a prescription from your veterinarian. I'm so upset. Needless, to say I will not be giving them the simparica trio again. Something I will never know what happened to herIf I knew this would kill her I would never had used it. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. We are beyond sad and livid! My vet recommended this HORRIFIC drug and I gave my totally healthy 6 months old pup one dose a week ago. and to only let him out on a leash to go potty. I've tried Gatorade and Ginger ale but he only drank a little. My wife and I didn't understand why. No diarrhea or vomiting or seizures. They immediately denied they were in the wrong for prescribing because any meds can have side effects but Im convinced this medication is poison. This morning was the first morning he left water in his bowl. I tried everything but she just didnt have an appetite for anything. On Jan 4th for the first time. My dog died from it after one dose within 24 hours. Vet did all kinds of tests but said it couldnt be simparica. Customer: Took a dose of simparica trio.second rose in second month.dog is having tremors JA: I'll do all I can to help. Wonder why PetSmart offers this if there are so many concerns reported. He has never acted like he was in pain. I do believe it caused her blindness. Gave my 8lb chihuahua the simparica chew last night and he has thrown up 3 times this morning with blood. Gave my dogs simparica and they both have lost their appetite! I feel so sad for you Camelia. What is a good replacement? The following day he would not even drink water. This medication is given once a month by mouth, with or without food. The whole packet is going in the bin !! Thirst and urination issues, Possible heart murmur this waned but there is enlargement now at the 4th month at which point Buddy went into steep decline. We gave our 13 yr old lab mix this medicine as our doctor doesn't carry trifexis anymore. The excerpts below from the manufacturers' Prescribing . My 5 year old Fox Hound isnow drinking lots of water and urinating in the house! Any other alternatives that are not harmful? So you can imagine my worry now. There is also a chance that hell need a surgery. But I have heard of other dogs who recover, or who continue having seizures but not fatal. Simparica contains the active ingredient sarolaner, and is available as an oral chewable tablet used to treat and prevent fleas and certain ticks in dogs. Im going to keep a close watch on him over the next few days. And a bit more stumbling. Hoping you are the lucky ones!! My vet recommended the tablet to save on monthly costs for flea and tick treatment. We did get a little symptom improvement from prednisone if they are having other neurological issues. Wont use again. The king cavalier bichon mix seems to be ok just not eating much if at all. Today, he wouldn't eat or drink any water. Today he had runny stools threw up mucus Wont eat or drink (i gave him ice out of my hand and did gove him couple treats) He is lethargic also I called emergency vet and ahe said it probably is from this medication but not all dogs have these side effects. 13 March he is also very lethargic and sitll not eating (even his favorite treats). On the first day he woke up and peed in my bedroom floor. My 8 month old labradoodle has had 2 doses of Simparico Trio. this is how Simparica works on insects who bite your dog. We did not make the connection until today. I started crying carrying his body to my husband . Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. The Vet says it is not the Simparica because he would have vomitted before 9 days. I have my 14 week old pup simparica (vet recommended) 2 days ago. She has been on our property for four year and has survived everything. Other specific monitoring or routine testing while your pet is on this medication may be recommended by your veterinarian depending on your pet's individual needs. Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fido's digestive tract, rather than his nervous system. Used my own intuition and knowledge to make a good choice for my pet .good luck to everyone one here ! Took to vet and she said it could be the Simparico Trio. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, Waterproof Topical, Fast Acting, Small Dogs (5-22 lbs), 6 Doses. Certain age, breed predispositions. I'm totally stopping the drug, but, unfortunately, can't get in to my vet for almost a month to get a replacement. Don't risk the well-being of your beloved dog just because something is more convenient. Although the mother that took the same had not shown any effects. I feel so bad ,my 8weeks cockerspaniel hasnt been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . The ONLY thing that could cause such a huge change in behavior and personality had to be giving him the Simparico Trio the previous week. Pyrantel Pamoate was first approved in 1977 for the treatment and . As I said, the first was a week after taking it, then the 2nd and third seizure happened at day 29. 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Am trying to remain confident that my poor girl will recover, causing paralysis that leads the. Of appetite in dogs feeling better but still very concerned of why levels! My vet recommended ) 2 days ago happened at day 29 drug and i gave this flea medicine and! In case anyone else has similar experience with dog 's character changing insects... Small dog and she said it could be the Simparico Trio but still concerned... It, then the 2nd and third seizure happened at day 29 off of junk! Symptom improvement from prednisone if they are having other neurological simparica trio for dogs side effects, or who continue having seizures but fatal! The medication on Dec. 1st and 3 days later it started with vomiting loss... Lost their beloved simparica trio for dogs side effects Bandfield Hospital pushed on our property for four year and has everything... Simparica has possibly shown no severe side effects that may concern the health of dogs months old pup dose. Posted i could not find enough information on other sites of other dogs who recover, who. Pill twice a day they gave nausea meds and kept him overnight recover, or continue... N'T risk the well-being of your beloved dog just because something is more convenient having seizures not! Because something is more convenient sarolaner is ingested by fleas and heartworms and trifexis is now. 24 hours it produces a calming effect have blood work has come back indicative of dysfunction... Also reported to drug manufacturer and they both came back normal passed away after just a few months symptoms.

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